Activating natural product synthesis using CRISPR interference and activation systems in Streptomyces
Author:
Affiliation:
1. Department of BioSciences, Rice University , 6100 Main Street , MS 140, Houston , TX 77005, USA
2. Department of Bioengineering, Rice University , 6100 Main Street , MS 142, Houston , TX 77005, USA
Abstract
Funder
Welch Foundation
Alfred P. Sloan Research Fellowship
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
https://academic.oup.com/nar/article-pdf/50/13/7751/45034036/gkac556.pdf
Reference72 articles.
1. Antibiotic resistance: a rundown of a global crisis;Aslam;Infect. Drug Resist.,2018
2. The future of antibiotics and resistance;Spellberg;N. Engl. J. Med.,2013
3. Discovery of microbial natural products by activation of silent biosynthetic gene clusters;Rutledge;Nat. Rev. Microbiol.,2015
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