1. The Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre , 351 Taché Avenue, Winnipeg, Manitoba R2H 2H6 , Canada
2. Department of Physiology and Pathophysiology, Rady College of Medicine, University of Manitoba , 351 Taché Avenue, Winnipeg, Manitoba R2H 2H6 , Canada
3. Department of Pharmacology and Therapeutics, Max Rady Faculty of Health Sciences, Rady College of Medicine, University of Manitoba , 351 Taché Avenue, Winnipeg, Manitoba R2H 2H6 , Canada