1. Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University , Bobrzynskiego 14, Krakow 30-348 , Poland
2. Department of Pharmacology, Jagiellonian University Medical College , Grzegorzecka 16, 31-531 Krakow , Poland
3. The William Harvey Research Institute, Queen Mary University of London, Charterhouse Square , London EC1M 6BQ , UK