1. Centre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology and Pharmacology , University College London, Gower Street, London WC1E 6BT , UK
2. Centre for Clinical Pharmacology and Precision Medicine, William Harvey Research Institute, Queen Mary University of London , London , UK
3. Division of Cardiovascular Sciences, University of Manchester , Manchester , UK
4. Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London , London , UK