Factors influencing medium- and long-term occupational impact following COVID-19

Author:

O’Sullivan O12ORCID,Houston A1ORCID,Ladlow P13ORCID,Barker-Davies R M14ORCID,Chamley R56,Bennett A N17ORCID,Nicol E D89ORCID,Holdsworth D A6810ORCID

Affiliation:

1. Academic Department of Military Rehabilitation (ADMR), Defence Medical Rehabilitation Centre (DMRC) , Stanford Hall, Loughborough LE12 5QW , UK

2. Academic Unit of Injury, Recovery and Inflammation Science, School of Medicine, University of Nottingham , Nottingham NG7 2RD , UK

3. Department for Health, University of Bath , Bath BA2 7AY , UK

4. School of Sport, Exercise and Health Sciences, Loughborough University , Loughborough LE11 3TU , UK

5. Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford , Oxford OX3 9DU , UK

6. Royal Centre for Defence Medicine , Birmingham B15 2GW , UK

7. National Heart and Lung Institute, Imperial College London , London SW7 2BX , UK

8. Academic Department of Military Medicine , Birmingham B15 2GW , UK

9. School of Biomedical Engineering & Imaging Sciences, King’s College London , London WC2R 2LS , UK

10. Oxford University Hospitals NHS Foundation Trust , Oxford OX3 9DU , UK

Abstract

Abstract Background Significant numbers of individuals struggle to return to work following acute coronavirus disease 2019 (COVID-19). The UK Military developed an integrated medical and occupational pathway (Defence COVID-19 Recovery Service, DCRS) to ensure safe return to work for those with initially severe disease or persistent COVID-19 sequalae. Medical deployment status (MDS) is used to determine ability to perform job role without restriction (‘fully deployable’, FD) or with limitations (‘medically downgraded’, MDG). Aims To identify which variables differ between those who are FD and MDG 6 months after acute COVID-19. Within the downgraded cohort, a secondary aim is to understand which early factors are associated with persistent downgrading at 12 and 18 months. Methods Individuals undergoing DCRS had comprehensive clinical assessment. Following this, their electronic medical records were reviewed and MDS extracted at 6, 12 and 18 months. Fifty-seven predictors taken from DCRS were analysed. Associations were sought between initial and prolonged MDG. Results Three hundred and twenty-five participants were screened, with 222 included in the initial analysis. Those who were initially downgraded were more likely to have post-acute shortness of breath (SoB), fatigue and exercise intolerance (objective and subjective), cognitive impairment and report mental health symptoms. The presence of fatigue and SoB, cognitive impairment and mental health symptoms was associated with MDG at 12 months, and the latter two, at 18 months. There were also modest associations between cardiopulmonary function and sustained downgrading. Conclusions Understanding the factors that are associated with initial and sustained inability to return to work allows individualized, targeted interventions to be utilized.

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health

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