1. MRC Versus Arthritis Centre for Musculoskeletal Health and Work, University of Southampton SO16 6YD , Southampton , UK
2. MRC Lifecourse Epidemiology Centre, University of Southampton , Southampton SO16 6YD , UK
3. Monash Centre for Occupational and Environmental Health, Monash University , Melbourne , Australia
4. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford , Oxford OX3 7LD , UK
5. National Institute for Health Research Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust , Southampton SO16 6YD , UK