1. Department of Biotechnology and Translational Medicine, University of Milan , Milan 20010 , Italy
2. Institute of Metabolism and Systems Research, University of Birmingham , Birmingham B152TT , United Kingdom
3. Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners , Birmingham B152TT , United Kingdom
4. Department of Endocrinology, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust , Birmingham B152GW , United Kingdom
5. NIHR Birmingham Biomedical Research Centre, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust , Birmingham B152GW , United Kingdom
6. Department of Clinical Sciences and Community Health, University of Milan , Milan 20100 , Italy
7. Institute of Inflammation and Ageing, University of Birmingham , Birmingham B152TT , United Kingdom
8. The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford , Oxford OX37FY , United Kingdom
9. Institute of Clinical Sciences, University of Birmingham , Birmingham B152TT , United Kingdom
10. Unit of Endocrinology, Ospedale Niguarda Cà Granda , Milan 20100 , Italy