Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection-Reference-Cited by-同舟云学术

Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection

Published:2017 Issue:3 Volume:4 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Fischer William A¹,Brown Jerry²,Wohl David Alain³,Loftis Amy James³,Tozay Sam²,Reeves Edwina²,Pewu Korto²,Gorvego Galapaki²,Quellie Saturday⁴,Cunningham Coleen K⁵,Merenbloom Carson³,Napravnik Sonia³,Dube Karine⁶,Adjasoo David⁷,Jones Erin⁷,Bonarwolo Korlia⁸,Hoover David⁷

Affiliation:

1. Divisions of Pulmonary and Critical Care Medicine and

2. Eternal Love Winning Africa Hospital, Monrovia, Liberia

3. Infectious Disease and

4. Phebe Hospital & School of Nursing, Suakoko, Bong County, Liberia

5. Department of Pediatrics, Duke University Medical Center, Durham, North Carolina

6. Public Health Leadership Program, The University of North Carolina at Chapel Hill

7. Clinical Research Management, Inc. (ClinicalRM), Hinckley, Ohio; and

8. Ebola Survivor Association of Liberia Inc, Monrovia

Abstract

Abstract Among 149 men who survived Ebola virus disease (EVD) and donated semen 260–1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/4/3/ofx155/33622866/ofx155.pdf

Reference19 articles.

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3. Molecular evidence of sexual transmission of Ebola virus;Mate;N Engl J Med,2015