Characteristics and Mortality of Pneumocystis Pneumonia in Patients With Cushing’s Syndrome: A Plea for Timely Initiation of Chemoprophylaxis-Reference-Cited by-同舟云学术

Characteristics and Mortality of Pneumocystis Pneumonia in Patients With Cushing’s Syndrome: A Plea for Timely Initiation of Chemoprophylaxis

Published:2017-01-01 Issue:1 Volume:4 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

van Halem Karlijn¹,Vrolijk Lucia¹,Pereira Alberto Martin²,de Boer Markus Gerardus Johannes¹

Affiliation:

1. Department of Infectious Diseases and

2. Department of Medicine, Division of Endocrinology, and Center for Endocrine Tumors, Leiden University Medical Center, The Netherlands

Abstract

Abstract In patients with Cushing’s syndrome, development of Pneumocystis pneumonia (PCP) is associated with extreme cortisol production levels. In this setting, immune reconstitution after abrogation of cortisol excess appears to induce development of symptomatic PCP. The high mortality rate warrants timely initiation of chemoprophylaxis or even preemptive treatment of PCP.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/4/1/ofx002/33622572/ofx002.pdf

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