Tigecycline as a Second-Line Agent for Legionnaires’ Disease in Severely Ill Patients-Reference-Cited by-同舟云学术

Tigecycline as a Second-Line Agent for Legionnaires’ Disease in Severely Ill Patients

Published:2017 Issue:4 Volume:4 Page:
ISSN:2328-8957
Container-title:Open Forum Infectious Diseases
language:en
Short-container-title:

Author:

Slawek Deepika¹,Altshuler Diana²,Dubrovskaya Yanina²,Louie Eddie¹

Affiliation:

1. Division of Infectious Diseases, NYU Langone Medical Center, New York, New York

2. Department of Pharmacy, NYU Langone Medical Center, New York, New York

Abstract

Abstract Treatment of Legionnaires’ disease in severely ill or immunosuppressed patients presents a clinical challenge. Tigecycline (TG) achieves high concentrations intracellularly and has been shown to be effective against L. pneumophila in animal and cell models. We report our experience using TG as second-line therapy. Clinical response was seen in most patients after switching to TG alone or as a combination therapy.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Link

http://academic.oup.com/ofid/article-pdf/4/4/ofx184/33624038/ofx184.pdf

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