Pleural Effusion Caused by Bacillus Calmette-Guérin Immunotherapy for Bladder Cancer

Author:

Rachakonda Tara1,Kendall Brian2,Spivak Adam M2,Boltax Jonathan3

Affiliation:

1. Department of Medicine

2. Division of Infectious Disease, and

3. Division of Pulmonary Medicine, University of Utah Hospital & Clinics and Huntsman Cancer Hospital, Salt Lake City

Abstract

Abstract Intravesical bacillus Calmette Guérin (BCG) instillation has been used as immunotherapy for early stage bladder cancer for >40 years. Complications from this therapy are rare but may result in a spectrum of infectious sequelae. Here we describe the case of an elderly man who presented with a pleural effusion and subcutaneous nodule several years after treatment with BCG.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference19 articles.

1. World Health Organization. BCG vaccine: WHO position paper;Wkly Epidemiol Rec,2004

2. Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature;Pérez-Jacoiste Asín;Medicine (Baltimore),2014

3. Spectrum of bacille Calmette-Guérin (BCG) infection after intravesical BCG immunotherapy;Gonzalez;Clin Infect Dis,2003

4. Risk of complications during endovesical treatment with BCG for superficial tumor of the bladder;Allouc;Presse Med,1997

5. BCGiosis as a presenting feature of a child with chronic granulomatous disease;Movahedi;Braz J Infect Dis,2011

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