Acute Human Immunodeficiency Virus (HIV) Infection Presenting With Bilateral Interstitial Pneumonia: Case Report and Discussion of Potential HIV-Induced Interstitial Pneumonia

Author:

Peri Anna Maria1,Alagna Laura1,Trovati Serena1,Sabbatini Francesca1,Rona Roberto2,Simonetti Francesco Roberto3,Foresti Sergio1,Migliorino Guglielmo Marco1,Gori Andrea1,Bandera Alessandra1

Affiliation:

1. Division of Infectious Diseases, San Gerardo Hospital, Monza, Italy

2. Intensive Care Unit, San Gerardo Hospital, Monza, Italy

3. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland

Abstract

Abstract A 50-year-old man was admitted to intensive care unit because of acute respiratory failure due interstitial pneumonia; after admission, a diagnosis of acute human immunodeficiency virus (HIV)-1 infection was made. Clinical and radiological improvement was observed only after introduction of antiretroviral treatment. We discuss the hypothesis of interstitial pneumonia induced by the acute HIV-1 infection.

Funder

Gilead Sciences and Associazione Nazionale Lotta Contro l’AIDS

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference15 articles.

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3. Impact of antiretroviral therapy on lung immunology and inflammation;Twigg;Clin Chest Med,2013

4. The complexity of HIV persistence and pathogenesis in the lung under antiretroviral therapy: challenges beyond AIDS;Almodovar;Viral Immunol,2014

5. Healthy HIV-1-infected individuals on highly active antiretroviral therapy harbor HIV-1 in their alveolar macrophages;Cribbs;AIDS Res Hum Retroviruses,2015

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