Successful Pre- and Posttransplant Sofosbuvir-Based Anti-Hepatitis C Virus Treatment in Persons Living With Human Immunodeficiency Virus Infection

Author:

Guaraldi Giovanni1,Rossotti Roberto2,Verucchi Gabriella3,Tavio Marcello4,Pasulo Luisa5,Beghetto Barbara1,Dolci Giovanni1,Nardini Giulia1,Badia Lorenzo3,Magliano Anna4,Moioli Maria Cristina2,Puoti Massimo2,Travi Giovanna,Pazzi Annamaria,De Carlis Luciano,Giacomoni Alessandro,Lauterio Andrea,Mangoni Iacopo,Di Sandro Stefano,Ferla Fabio,Fagiuoli Stefano,Colledan Michele,Cologni Giuliana,Di Benedetto Fabrizio,Tarantino Giuseppe,Serra Valentina,Dolci Giovanni,

Affiliation:

1. Infectious Diseases Departments of University of Modena, Italy

2. ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy

3. University of Bologna, Italy

4. Azienda Ospedaliera Universitaria Ospedali Riuniti, Ancona, Italy; and

5. Gastroenterology Department ASST Papa Giovanni XXIII, Bergamo, Italy

Abstract

Abstract This retrospective study reports the data of sofosbuvir-based anti-hepatitis C virus treatment in 24 candidates and 24 recipients of liver transplantation coinfected with human immunodeficiency virus. Sustained virologic response was cumulatively 85% (90% and 100% in those treated with optimal schedules pre- and posttransplant, respectively).

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

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