Affiliation:
1. Department of Internal Medicine, Section on Infectious Disease, Wake Forest University School of Medicine , Winston-Salem, North Carolina, USA
Abstract
Abstract
Case detection through contact tracing is a key intervention during an infectious disease outbreak. However, contact tracing is an intensive process where a given contact tracer must locate not only confirmed cases but also identify and interview known contacts. Often these data are manually recorded. During emerging outbreaks, the number of contacts could expand rapidly and beyond this, when focused on individual transmission chains, larger patterns may not be identified. Understanding if particular cases can be clustered and linked to a common source can help to prioritize contact tracing effects and understand underlying risk factors for large spreading events. Electronic health records systems are used by the vast majority of private healthcare systems across the USA, providing a potential way to automatically detect outbreaks and connect cases through already collected data. In this analysis, we propose an algorithm to identify case clusters within a community during an infectious disease outbreak using Bayesian probabilistic case linking and explore how this approach could supplement outbreak responses; especially when human contact tracing resources are limited.
Publisher
Oxford University Press (OUP)
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology