1. Academic Unit of Injury, Recovery and Inflammation Sciences (IRIS), School of Medicine , University of Nottingham, Nottingham, UK
2. NIHR Applied Research Collaboration East Midlands (ARC-EM) , Nottingham, UK
3. University of Nottingham NIHR Nottingham Biomedical Research Centre , , Nottingham NG7 2UH , UK
4. Nottingham University Hospitals NHS Trust Queen's Medical Centre Campus Ringgold Standard Institution , Nottingham NG7 2UH , UK