Nutrition for dementia prevention: a state of the art update for clinicians

Author:

Townsend Rebecca1,Fairley Andrea1,Gregory Sarah23,Ritchie Craig234,Stevenson Emma1,Shannon Oliver M5ORCID

Affiliation:

1. Newcastle University School of Biomedical, Nutritional and Sport Sciences, Human Nutrition & Exercise Research Centre, , Newcastle upon Tyne, UK

2. University of Edinburgh Edinburgh Dementia Prevention, Centre for Clinical Brain Sciences, , Edinburgh, UK

3. Scottish Brain Sciences , Edinburgh, UK

4. University of St Andrews Brain Health and Neurodegenerative Medicine, Mackenzie Institute, , St Andrews, UK

5. Newcastle University Human Nutrition & Exercise Research Centre, Population Health Sciences Institute, Centre for Healthier Lives, , Newcastle upon Tyne, UK

Abstract

Abstract Background and objectives Dementia prevalence continues to rise. It is therefore essential to provide feasible and effective recommendations to encourage healthy brain ageing and reduce dementia risk across the population. Appropriate nutrition represents a potential strategy to mitigate dementia risk and could be recommended by clinicians as part of mid-life health checks and other health initiatives to reduce dementia prevalence. The purpose of this review is to provide a clinician-focused update on the current state of the knowledge on nutrition and dementia prevention. Methods Narrative review. Results Strong evidence exists to support the consumption of healthy, plant-based dietary patterns (e.g. Mediterranean, MIND or Nordic diet) for maintaining cognitive function and reducing dementia risk in later life and is supported by dementia prevention guideline from leading public health bodies (e.g. World Health Organization). Emerging evidence suggests potential cognitive benefits of consuming specific nutrients/foods (e.g. n-3 fatty acids or fish, flavonols and B-vitamins) and multi-nutrient compounds (e.g. Fortasyn Connect). Challenges and opportunities for integrating nutritional/dietary interventions for dementia prevention into clinical practice are explored in this review. Conclusions Appropriate nutrition represents an important factor to help facilitate healthy cognitive ageing and allay dementia risk. The information provided in this article can help clinicians provide informed opinions on appropriate nutritional strategies as part of mid-life Health Checks and other risk reduction initiatives.

Funder

Scottish Brain Sciences

NuBrain grant

National Institute for Health Research

Biotechnology and Biological Sciences Research Council

Medical Research Council

UK Nutrition Research Partnership

Publisher

Oxford University Press (OUP)

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