Resistant syndrome of inappropriate antidiuretic hormone (SIADH) secondary to atonic bladder in an older woman

Author:

Hogan Patrick C P1ORCID,McGauran Jane1,O’Brien Helen1,Rolston Amy1,O’Neill Desmond2ORCID

Affiliation:

1. Tallaght University Hospital—Department of Age-Related Healthcare, Dublin, Ireland

2. Trinity College Dublin—Centre for Ageing, Neuroscience and the Humanities, Trinity Centre for Health Sciences Tallaght Hospital, Dublin 24, Ireland

Abstract

Abstract Syndrome of inappropriate antidiuretic hormone (SIADH) is the most common cause of hyponatraemia. There are many causes of SIADH, but investigation tends to focus around the most common causes—particularly diseases of the brain and lung, malignancy and medication-induced SIADH [Ellison and Berl (2007, The Syndrome of Inappropriate Antidiuresis. N Engl J Med., 356, 2064–72]. We describe a case of SIADH secondary to atonic bladder in an 83-year old woman, which was discovered on MRI of the abdomen, performed for further characterisation of a known pancreatic lesion. Insertion of a urinary catheter alleviated retention and resulted in prompt resolution of hyponatraemia. This is an under-recognised cause of this common condition, with important implications for investigation and management.

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Ageing,General Medicine

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