A mixed-methods study on the pharmacological management of pain in Australian and Japanese nursing homes

Author:

Dowd Laura A12ORCID,Hamada Shota345678,Hattori Yukari96,Veal Felicity C1011,Taguchi Reina34,Sakata Nobuo7812,Jadczak Agathe D13141514,Visvanathan Renuka15141617,Koujiya Eriko1819,Rajan Madhu2021,Doube Stefan22,Suzuki Ai78,Bernoth Maree232425,Rawson Helen26,Maruoka Hiroshi27,Wood Amelia28,Wagner Jo29,Hull Dee-Anne30,Katsuhisa Mizuki1819,Turner Justin123132,Liau Shin J121514ORCID,Reeve Emily1233ORCID,Bell J Simon121514,Cross Amanda J12ORCID

Affiliation:

1. Centre for Medicine Use and Safety (CMUS) , Faculty of Pharmacy and Pharmaceutical Sciences, , Parkville, Victoria , Australia

2. Monash University , Faculty of Pharmacy and Pharmaceutical Sciences, , Parkville, Victoria , Australia

3. Research Department , Institute for Health Economics and Policy, , Tokyo , Japan

4. Association for Health Economics Research and Social Insurance and Welfare , Institute for Health Economics and Policy, , Tokyo , Japan

5. Department of Home Care Medicine , Graduate School of Medicine, , Tokyo , Japan

6. The University of Tokyo , Graduate School of Medicine, , Tokyo , Japan

7. Department of Health Services Research , Institute of Medicine, , Tsukuba , Japan

8. University of Tsukuba , Institute of Medicine, , Tsukuba , Japan

9. Department of Geriatric Medicine , Graduate School of Medicine, , Tokyo , Japan

10. Unit for Medication Outcomes Research & Education (UMORE) , School of Pharmacy and Pharmacology, , Hobart, Tasmania , Australia

11. University of Tasmania , School of Pharmacy and Pharmacology, , Hobart, Tasmania , Australia

12. Heisei Medical Welfare Group Research Institute , Tokyo , Japan

13. Adelaide Geriatrics Training and Research with Aged Care (GTRAC) Centre , Adelaide Medical School, Faculty of Health and Medical Sciences, , Adelaide, South Australia , Australia

14. University of Adelaide , Adelaide Medical School, Faculty of Health and Medical Sciences, , Adelaide, South Australia , Australia

15. National Health and Medical Research Council (NHMRC) Centre of Research Excellence in Frailty and Healthy Ageing , Adelaide Medical School, Faculty of Health and Medical Sciences, , Adelaide, South Australia , Australia

16. Aged and Extended Care Services , The Queen Elizabeth Hospital, , Adelaide, South Australia , Australia

17. Central Adelaide Local Health Network , The Queen Elizabeth Hospital, , Adelaide, South Australia , Australia

18. Division of Health Sciences , Graduate School of Medicine, , Osaka , Japan

19. Osaka University , Graduate School of Medicine, , Osaka , Japan

20. Royal Australian College of General Practitioners , Victoria , Australia

21. Aged Care GP , Melbourne, Victoria , Australia

22. Transform Physio , Hobart, Tasmania , Australia

23. Charles Sturt University , Wagga Wagga, New South Wales , Australia

24. Three Rivers Department of Rural Health , Wagga Wagga, New South Wales , Australia

25. Murrumbidgee Primary Health Network Aged Care Consortium , Wagga Wagga, New South Wales , Australia

26. Nursing and Midwifery, Monash University , Clayton, Victoria , Australia

27. Yokohama Aobanosato Geriatric Health Services Facility , Yokohama , Japan

28. Longridge Aged Care , Naracoorte, South Australia , Australia

29. Australian Nursing and Midwifery Federation (SA Branch) , Adelaide, South Australia , Australia

30. Southern Cross Care (SA, NT and VIC), Glenside , South Australia , Australia

31. Centre de Recherche, Institue Universitaire de Gériatrie de Montréal , Montréal, Québec , Canada

32. Faculté de Pharmacie, Université Laval , Québec city, Québec , Canada

33. Quality Use of Medicines and Pharmacy Research Centre, University of South Australia: Clinical and Health Sciences , Adelaide, South Australia , Australia

Abstract

Abstract Background Understanding how analgesics are used in different countries can inform initiatives to improve the pharmacological management of pain in nursing homes. Aims To compare patterns of analgesic use among Australian and Japanese nursing home residents; and explore Australian and Japanese healthcare professionals’ perspectives on analgesic use. Methods Part one involved a cross-sectional comparison among residents from 12 nursing homes in South Australia (N = 550) in 2019 and four nursing homes in Tokyo (N = 333) in 2020. Part two involved three focus groups with Australian and Japanese healthcare professionals (N = 16) in 2023. Qualitative data were deductively content analysed using the World Health Organization six-step Guide to Good Prescribing. Results Australian and Japanese residents were similar in age (median: 89 vs 87) and sex (female: 73% vs 73%). Overall, 74% of Australian and 11% of Japanese residents used regular oral acetaminophen, non-steroidal anti-inflammatory drugs or opioids. Australian and Japanese healthcare professionals described individualising pain management and the first-line use of acetaminophen. Australian participants described their therapeutic goal was to alleviate pain and reported analgesics were often prescribed on a regular basis. Japanese participants described their therapeutic goal was to minimise impacts of pain on daily activities and reported analgesics were often prescribed for short-term durations, corresponding to episodes of pain. Japanese participants described regulations that limit opioid use for non-cancer pain in nursing homes. Conclusion Analgesic use is more prevalent in Australian than Japanese nursing homes. Differences in therapeutic goals, culture, analgesic regulations and treatment durations may contribute to this apparent difference.

Funder

Healthy Ageing Research Consortium

South Australian Department for Innovation and Skills

Hospital Research Foundation and Resthaven Inc

JSPS KAKENHI

Monash University

NHMRC

NHMRC Boosting Dementia Research Leadership Fellowship

National Health and Medical Research Council

Publisher

Oxford University Press (OUP)

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