Association between changes in diet quality from mid-life to late-life and healthy ageing: the Singapore Chinese Health Study

Author:

Zhou Yan-Feng1,Lai Jun S2,Chong Mary Foong-Fong23,Tong Eunice Huiying3,Neelakantan Nithya3,Pan An14,Koh Woon-Puay56

Affiliation:

1. Huazhong University of Science and Technology Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, , Wuhan, China

2. Singapore Institute for Clinical Sciences , Agency for Science, Technology, and Research, Singapore, Singapore

3. National University of Singapore and National University Health System Saw Swee Hock School of Public Health, , Singapore, Singapore

4. University of Chinese Academy of Sciences Key Laboratory of Systems Health Science of Zhejiang Province, Hangzhou Institute for Advanced Study, , Hangzhou, China

5. National University of Singapore Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, , Singapore, Singapore

6. Singapore Institute for Clinical Sciences , Agency for Science Technology and Research (A * STAR), Singapore, Singapore

Abstract

Abstract Background Few studies have evaluated the association between changes in diet quality from mid-life to late-life and healthy ageing. Methods We included 12,316 Chinese adults aged 45–74 years at baseline (1993–1998) from the Singapore Chinese Health Study. Diet quality was measured using the Dietary Approaches to Stop Hypertension (DASH) scores at baseline and follow-up 3 interviews (2014–2016). Healthy ageing was assessed at follow-up 3 interviews, and was defined as absence of specific chronic diseases, good mental and overall self-perceived health, good physical functioning and absence of cognitive impairment, limitations in instrumental activities of daily living or function-limiting pain. Multivariable-adjusted logistic regression models were applied to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between changes in DASH scores and healthy ageing. Results Compared with participants who maintained relatively stable DASH scores, a >10% decrease in DASH score was associated with a 16% (95% CI, 4–26%) lower likelihood of healthy ageing, whereas a >10% increase in DASH score was associated with a 19% (95% CI, 3–37%) higher likelihood of healthy ageing. Compared with participants who were in the low-score group consistently, participants who increased their DASH scores from moderate-score at baseline to high-score at follow-up 3 had a 53% (95% CI, 21–92%) higher likelihood of healthy ageing, whereas those who were in the high-score group consistently had 108% (95% CI, 71–152%) higher likelihood of healthy ageing. Conclusions Improving diet quality from mid- to late-life was associated with a higher likelihood of healthy ageing.

Funder

National Medical Research Council

National Natural Science Foundation of China

National University of Singapore

Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Aging,General Medicine

Reference35 articles.

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