The impact of frailty on patient-reported outcomes following hip and knee arthroplasty

Author:

Cook Michael J1ORCID,Lunt Mark1,Ashcroft Darren M23,Board Timothy4,O’Neill Terence W15

Affiliation:

1. University of Manchester Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology Medicine and Health, , Manchester, UK

2. University of Manchester Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Manchester Academic Health Science Centre, , Manchester UK

3. University of Manchester NIHR Greater Manchester Patient Safety Translational Research Centre, Faculty of Biology, Medicine and Health, , Manchester, UK

4. Wrightington Hospital Department of Trauma and Orthopaedic Surgery, , Wigan, UK

5. Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre NIHR Manchester Biomedical Research Centre, , Manchester, UK

Abstract

Abstract Aim to determine the impact of frailty on patient-reported outcomes following hip and knee arthroplasty. Methods we used linked primary and secondary care electronic health records. Frailty was assessed using the electronic frailty index (categorised: fit, mild, moderate, severe frailty). We determined the association between frailty category and post-operative Oxford hip/knee score (OHS/OKS) using Tobit regression. We calculated the proportion of patients in each frailty category who achieved the minimally important change (MIC) in OHS (≥8 points) and OKS (≥7 points) and the proportion who reported a successful outcome (hip/knee problems either ‘much better’ or ‘a little better’ following surgery). Results About 42,512 people who had a hip arthroplasty and 49,208 who had a knee arthroplasty contributed data. In a Tobit model adjusted for pre-operative OHS/OKS, age, sex and quintile of index of multiple deprivation, increasing frailty was associated with decreasing post-operative OHS and OKS, respectively, β-coefficient (95% CI) in severely frail versus fit, −6.97 (−7.44, −6.49) and − 5.88 (−6.28, −5.47). The proportion of people who achieved the MIC in OHS and OKS, respectively, decreased from 92 and 86% among fit individuals to 84 and 78% among those with severe frailty. Patient-reported success following hip and knee arthroplasty, respectively, decreased from 97 and 93% among fit individuals to 90 and 83% among those with severe frailty. Conclusion frailty adversely impacts on patient-reported outcomes following hip and knee arthroplasty. However, even among those with severe frailty, the large majority achieved the MIC in OHS/OKS and reported a successful outcome.

Funder

NIHR

Versus Arthritis

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Aging,General Medicine

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