Frailty, hospital use and mortality in the older population: findings from the Newcastle 85+ study

Author:

Keeble Eilis1,Parker Stuart G2,Arora Sandeepa1,Neuburger Jenny3,Duncan Rachel2,Kingston Andrew2,Hanratty Barbara2,Jagger Carol2,Robinson Louise2,Kirkwood Tom4

Affiliation:

1. Nuffield Trust, London, UK

2. Newcastle University, Institute for Health and Society, Newcastle Institute for Ageing, Newcastle upon Tyne, UK

3. Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK

4. Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK

Abstract

Abstract Background Frailty is a significant determinant of health care utilisation and associated costs, both of which also increase with proximity to death. What is not known is how the relationships between frailty, proximity to death, hospital use and costs develop in a population aged 85 years and over. Methods This study used data from a prospective observational cohort, the Newcastle 85+ Study, linked with hospital episode statistics and death registrations. Using the Rockwood frailty index (cut off <0.25), we analysed the relationship between frailty and mortality, proximity to death, hospital use and hospital costs over 2, 5 and 7 years using descriptive statistics, Kaplan–Meier survival curves, Cox’s proportional hazards and negative binomial regression models. Results Baseline frailty was associated with a more than two-fold increased risk of mortality after 7 years, compared to people who were non-frail. Participants classified as frail spent more time in hospital over 7 years than the non-frail, but this difference declined over time. Baseline frailty was not associated with increased time spent in hospital during the last 90 days of life. Conclusion Evidence continues to accrue on the impact of frailty on emergency health care use. Hospital and community services need to adapt to meet the challenge of introducing new proactive and preventative approaches, designed to achieve benefits in clinical and/or cost effectiveness of frailty management.

Funder

National Institute for Health Research

NHS

National Institute on Handicapped Research

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Ageing,General Medicine

Reference30 articles.

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3. Frailty status at admission to hospital predicts multiple adverse outcomes;Hubbard,2017

4. A scoping review of frailty and acute care in middle-aged and older individuals with recommendations for future research;Hogan,2017

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