The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment

Author:

Brockmeier Erica K.1,Hodges Geoff2,Hutchinson Thomas H.3,Butler Emma2,Hecker Markus4,Tollefsen Knut Erik5,Garcia-Reyero Natalia67,Kille Peter8,Becker Dörthe9,Chipman Kevin9,Colbourne John9,Collette Timothy W.10,Cossins Andrew1,Cronin Mark11,Graystock Peter12,Gutsell Steve2,Knapen Dries13,Katsiadaki Ioanna14,Lange Anke15,Marshall Stuart2,Owen Stewart F.16,Perkins Edward J.6,Plaistow Stewart1,Schroeder Anthony17,Taylor Daisy18,Viant Mark9,Ankley Gerald19,Falciani Francesco1

Affiliation:

1. Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK

2. Safety and Environmental Assurance Centre, Unilever, Colworth Science Park, Sharnbrook MK44 1LQ, UK

3. School of Biological Sciences, University of Plymouth, Plymouth, Devon PL4 8AA, UK

4. Toxicology Centre and School of the Environment and Sustainability, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B3, Canada

5. Norwegian Institute for Water Research (NIVA), N-0349 Oslo, Norway

6. US Army Engineer Research and Development Center, Vicksburg, Mississippi

7. Mississippi State University, Institute for Genomics, Biocomputing and Biotechnology, Starkville, Mississippi

8. Cardiff School of Biosciences, University of Cardiff, Cardiff CF10 3AT, UK

9. School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

10. National Exposure Research Laboratory, U.S. Environmental Protection Agency, Athens, Georgia 30605-2700

11. School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK

12. Department of Entomology, University of California, Riverside, California 92521

13. Zebrafishlab, University of Antwerp, Universiteitsplein 1, Belgium

14. Centre for Environment, Fisheries and Aquaculture Science (CEFAS), The Nothe, Weymouth, Dorset DT4 8UB, UK

15. Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter EX4 4QD, UK

16. AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TF, UK

17. Water Resources Center (Office: Mid-Continent Ecology Division), University of Minnesota, Minnesota 55108

18. School of Biological Sciences, Life Sciences Building, University of Bristol, Bristol BS8 1TQ, UK;

19. U.S. Environmental Protection Agency, Duluth, Minnesota 55804

Funder

Natural Environment Research Council

Publisher

Oxford University Press (OUP)

Subject

Toxicology

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