Activation of Autophagy Rescues Amiodarone-Induced Apoptosis of Lung Epithelial Cells and Pulmonary Toxicity in Rats

Author:

Lee Kang-Yo,Oh Sehee,Choi You-Jin,Oh Seon-Hee,Yang Young-Su,Yang Mi-Jin,Lee Kyuhong,Lee Byung-Hoon

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference51 articles.

1. Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis;Autophagy,(2011)

2. Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling;PLoS One,(2009)

3. Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity;J. Pharmacol. Exp. Ther,(2001)

4. Distribution of amiodarone and its metabolite, desethylamiodarone, in human tissues;Can. J. Physiol. Pharmacol,(1987)

5. A morphometric study of mucins and small airway plugging in cystic fibrosis;Thorax,(2007)

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