Fatty-Acid Binding Protein 4 (FABP4) as a Potential Preclinical Biomarker of Drug-Induced Kidney Injury

Author:

Obajdin Jana12,Cotter Mabel13,Snelling Sara14,Dremier Sarah15,De Ron Pierrette1,Fleurance Renaud1,Valentin Jean-Pierre1,Nogueira da Costa André6,Gryshkova Vitalina1

Affiliation:

1. Department of Development Science, Investigative Toxicology

2. Centre for Stem Cells & Regenerative Medicine King’s College London, Tower Wing Guy’s Campus Great Maze Pond London SE1 9RT, UK

3. Safety & Environmental Assurance Centre, Unilever U.K., Unilever House, Blackfriars, London EC4Y 0DY, UK

4. Immunology, Abzena, Babraham Research Campus, Cambridge CB22 3AT, UK

5. Ogeda SA, 47 Rue Adrienne Bolland, Gosselies, Belgium 6041, Sarah Dremier

6. Department of Translational Medicine, Experimental Medicine and Diagnostics, UCB Biopharma SPRL, Chemin du Foriest 1, B-1420 Braine L'Alleud, Belgium

Funder

Walloon Region

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference40 articles.

1. Biomarkers of collecting duct injury in Han-Wistar and Sprague-Dawley rats treated with N-phenylanthranilic acid;Betton;Toxicol. Pathol.,2012

2. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease;Board;Kidney Int. Suppl,2013

3. Next-generation biomarkers for detecting kidney toxicity;Bonventre;Nat. Biotechnol.,2010

4. Lessons learned from the fate of AstraZeneca's drug pipeline: A five-dimensional framework;Cook;Nat. Rev. Drug Discov.,2014

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