Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling

Author:

Siegrist Katelyn J1,Romo DeeDee1,Upham Brad L2,Armstrong Michael3,Quinn Kevin3,Vanderlinden Lauren4,Osgood Ross S15,Velmurugan Kalpana1,Elie Marc3,Manke Jonathan3,Reinhold Dominik6,Reisdorph Nichole3,Saba Laura3,Bauer Alison K1

Affiliation:

1. Department of Environmental and Occupational Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado

2. Department of Pediatrics and Human Development, Michigan State University, East Lansing, Michigan

3. Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado

4. Department of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado

5. Harvard T.H. Chan School of Public Health, Cambridge

6. PPD, Wilmington, North Carolina

Funder

Flight Attendant Medical Research Institute

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference66 articles.

1. Arachidonic acid containing phosphatidylcholine increases due to microglial activation in ipsilateral spinal dorsal horn following spared sciatic nerve injury;Banno;PLoS One,2017

2. Benzo(a)pyrene induces lung toxicity and inflammation in mice: Prevention by carvacrol;Barnwal;Hum. Exp. Toxicol.,2018

3. Butylated hydroxytoluene (BHT) induction of pulmonary inflammation: A role in tumor promotion;Bauer;Exp. Lung Res.,2001

4. Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model;Bauer;Arch. Toxicol,2017

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