Resolving the Reversed Rate Effect of Calcium Channel Blockers on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and the Impact on In Vitro Cardiac Safety Evaluation-Reference-Cited by-同舟云学术

Resolving the Reversed Rate Effect of Calcium Channel Blockers on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and the Impact on In Vitro Cardiac Safety Evaluation

Published:2018-10-26 Issue:2 Volume:167 Page:573-580
ISSN:1096-6080
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Zeng Haoyu¹,Wang Jixin¹,Clouse Holly¹,Lagrutta Armando¹,Sannajust Frederick¹

Affiliation:

1. Safety and Exploratory Pharmacology, Merck & Co., Inc., West Point, Pennsylvania 19486-0004

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/167/2/573/27694615/kfy264.pdf

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3. High throughput measurement of Ca(2)(+) dynamics for drug risk assessment in human stem cell-derived cardiomyocytes by kinetic image cytometry;Cerignoli;J. Pharmacol. Toxicol. Methods,2012

4. The comprehensive in vitro proarrhythmia assay (CiPA) initiative - Update on progress;Colatsky;J. Pharmacol. Toxicol. Methods,2016

5. Comparison of antiarrhythmic and electrophysiologic effects of diltiazem and its analogue siratiazem;Guc;J. Cardiovasc. Pharmacol,1993

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