Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat

Author:

Fielden Mark R.1,Nie Alex2,McMillian Michael2,Elangbam Chandi S.3,Trela Bruce A.4,Yang Yi4,Dunn Robert T.5,Dragan Yvonne6,Fransson-Stehen Ronny7,Bogdanffy Matthew8,Adams Stephen P.910,Foster William R.910,Chen Shen-Jue910,Rossi Phil11,Kasper Peter12,Jacobson-Kram David13,Tatsuoka Kay S.3,Wier Patrick J.3,Gollub Jeremy14,Halbert Donald N.14,Roter Alan14,Young Jamie K.15,Sina Joseph F.16,Marlowe Jennifer17,Martus Hans-Joerg17,Aubrecht Jiri18,Olaharski Andrew J.1,Roome Nigel19,Nioi Paul20,Pardo Ingrid20,Snyder Ron20,Perry Richard21,Lord Peter2,Mattes William11,Car Bruce D.910, ,

Affiliation:

1. Roche Palo Alto, Palo Alto, California

2. Johnson & Johnson Pharmaceutical Research & Development, Raritan, New Jersey

3. GlaxoSmithKline, Research Triangle Park, North Carolina

4. Abbott Laboratories, Abbott Park, Illinois

5. Amgen, Thousand Oaks, California

6. AstraZeneca, Boston, Massachusetts

7. AstraZeneca, Södertälje, Sweden

8. Boehringer-Ingelheim, Ridgefield, Connecticut

9. Bristol-Myers Squibb, Princeton, New Jersey

10. Bristol-Myers Squibb, Wallingford, Connecticut

11. Critical Path Institute, Tucson, Arizona

12. Federal Institute for Drugs and Medical Devices, Bonn, Germany

13. Food and Drug Administration, Washington, DC

14. Iconix Biosciences, Mountain View, California

15. Lilly Research Laboratories, Eli Lilly and Company, Greenfield, Indiana

16. Merck Research Laboratories, West Point, Pennsylvania

17. Novartis Pharma AG, Basel, Switzerland

18. Pfizer, Groton, Connecticut

19. Sanofi-Aventis, Porcheville, France

20. Schering-Plough Research Institute, Summit, New Jersey

21. Wyeth Research, Chazy, New York

Publisher

Oxford University Press (OUP)

Subject

Toxicology

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