The Mycoestrogen Zearalenone Induces CYP3A through Activation of the Pregnane X Receptor
Author:
Publisher
Oxford University Press (OUP)
Subject
Toxicology
Link
http://academic.oup.com/toxsci/article-pdf/91/2/448/10977006/kfj163.pdf
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4. Brobst, D. E., Ding, X., Creech, K. L., Goodwin, B., Kelley, B., and Staudinger, J. L. (2004). Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J. Pharmacol. Exp. Ther.310,528–535.
5. Chen, C., Staudinger, J. L., and Klaassen, C. D. (2003). Nuclear receptor, pregnane x receptor, is required for induction of UDP-glucuronosyltransferases in mouse liver by pregnenolone-16{alpha}-carbonitrile. Drug Metab. Dispos.31,908–915.
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