Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity-Reference-Cited by-同舟云学术

Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity

Published:2018-07-30 Issue:1 Volume:166 Page:123-130
ISSN:1096-6080
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Battista Christina¹²^ORCID,Yang Kyunghee¹,Stahl Simone H³^ORCID,Mettetal Jerome T⁴,Watkins Paul B²,Siler Scott Q¹,Howell Brett A¹⁵

Affiliation:

1. DILIsym Services, Inc., Research Triangle Park, North Carolina

2. Division of Pharmacotherapy and Experimental Therapeutics, UNC Institute for Drug Safety Sciences, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

3. Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, Astra Zeneca R&D, Cambridge CB4 0WG, UK

4. Safety and ADME Translational Sciences, Drug Safety and Metabolism, IMED Biotech Unit, Astra Zeneca R&D, Waltham, Massachusetts

5. DILIsym Services, Inc., Six Davis Drive, PO BOX 12317, Research Triangle Park, NC 27709

Funder

DILI-sim Initiative

Research Participation Program at the Center for Drug Evaluation and Research

U.S. Food and Drug Administration

Oak Ridge Institute for Science and Education

U.S. Department of Energy and Food and Drug Administration

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/166/1/123/26183767/kfy191.pdf

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