Nrf2 Ameliorates DDC-Induced Sclerosing Cholangitis and Biliary Fibrosis and Improves the Regenerative Capacity of the Liver

Author:

Fragoulis Athanassios12ORCID,Schenkel Julia1,Herzog Miriam1,Schellenberg Tim1,Jahr Holger1,Pufe Thomas1,Trautwein Christian3,Kensler Thomas W4,Streetz Konrad L3,Wruck Christoph Jan1

Affiliation:

1. Department of Anatomy and Cell Biology

2. Molecular Tumor Biology, Department of General, Visceral and Transplantation Surgery

3. Department of Medicine III, Medical Faculty, Uniklinik RWTH Aachen University, 52074 Aachen, Germany

4. Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference52 articles.

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2. Nrf2 in health and disease: current and future clinical implications;Al-Sawaf;Clin. Sci. (Lond.),2015

3. Nrf2 protects against TWEAK-mediated skeletal muscle wasting;Al-Sawaf;Sci. Rep,2014

4. Nrf2 augments skeletal muscle regeneration after ischemia-reperfusion injury;Al-Sawaf;J. Pathol,2014

5. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2;Aleksunes;Toxicol. Appl. Pharmacol.,2008

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