A Risk Assessment Perspective: Application of Mode of Action and Human Relevance Frameworks to the Analysis of Rodent Tumor Data

Author:

Dellarco Vicki L.,Baetcke Karl

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference14 articles.

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2. Klaunig, J. Babich, M. A., Baetcke, K. P., Cook, J. C., Corton, J. C., David, R. M., DeLuca, J. G., Lai, D. Y., McKee, R. H., Peters, J. M., et al. (2003). PPARa agonist-induced rodent tumors: Mode(s) of action and human relevance. Crit. Rev. Toxicol.33,655–780.

3. Hill, A. B. (1965). The environment and disease: Association or causation? Proc. R. Soc. Med.58,295–300.

4. USHHS (U.S. Department of Health and Human Services). (1982). The health consequences of smoking—Cancer, A Report of the Surgeon General. U.S. Department of Health and Human Services, Washington, D.C., pp. 17–20, 29 et seq.

5. Faustman, E., Ponce, R. A., Seeley, M. R., and Whittaker, S. G. (1997). Experimental approaches to evaluate mechanisms of developmental toxicity. In Handbook of Developmental Biology. (Hood, R. D., Ed.) Boca Raton, FL, CRC Press, pp. 13–41.

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