Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation-Reference-Cited by-同舟云学术

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Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation

Published:2019-02-15 Issue:2 Volume:169 Page:365-379
ISSN:1096-6080
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Song Gina¹,Moreau Marjory¹,Efremenko Alina¹,Lake Brian G²,Wu Huali³⁴,Bruckner James V⁵,White Catherine A⁵,Osimitz Thomas G⁶,Creek Moire R⁷⁸,Hinderliter Paul M⁹,Clewell Harvey J¹¹⁰,Yoon Miyoung¹¹¹

Affiliation:

1. ScitoVation, LLC, Research Triangle Park, North Carolina, 27709

2. Centre for Toxicology, University of Surrey, Surrey, UK

3. The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina

4. Duke Medical Center, Durham, North Carolina 27705

5. University of Georgia, Athens, Georgia 30602

6. Science Strategies LLC, Charlottesville, Virginia 22902

7. Valent USA, LLC, Walnut Creek, California 94596

8. Moire Creek Toxicology Consulting Services, Livermore, California 94550

9. Syngenta, Greensboro, North Carolina

10. Ramboll, Research Triangle Park, North Carolina 27709

11. ToxStrategies, Cary, North Carolina 27511

Funder

Advancement of Pyrethroid Human Risk Assessment

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/169/2/365/28745384/kfz042.pdf

Reference56 articles.

1. Influence of maturation on in vivo tissue to plasma partition coefficients for cis- and trans-permethrin;Amaraneni;J. Pharm. Sci.,2017

2. Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood-brain barrier maturation;Amaraneni;Neurotoxicology,2017

3. Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin;Amaraneni;Toxicol. Lett.,2016

4. Ontogeny of hepatic and plasma metabolism of deltamethrin in vitro: Role in age-dependent acute neurotoxicity;Anand;Drug Metab. Dispos.,2006

5. Age-dependent absolute abundance of hepatic carboxylesterases (CES1 and CES2) by LC-MS/MS proteomics: Application to PBPK modeling of oseltamivir in vivo pharmacokinetics in infants;Boberg;Drug Metab. Dispos.,2017

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