N-Alkylprotoporphyrin Formation and Hepatic Porphyria in Dogs After Administration of a New Antiepileptic Drug Candidate: Mechanism and Species Specificity-Reference-Cited by-同舟云学术

N-Alkylprotoporphyrin Formation and Hepatic Porphyria in Dogs After Administration of a New Antiepileptic Drug Candidate: Mechanism and Species Specificity

Published:2014-10-01 Issue:2 Volume:141 Page:353-364
ISSN:1096-0929
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Nicolas Jean-Marie,Chanteux Hugues,Mancel Valérie,Dubin Guy-Marie,Gerin Brigitte,Staelens Ludovicus,Depelchin Olympe,Kervyn Sophie

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/141/2/353/10915861/kfu131.pdf

Reference65 articles.

1. Metabolic activation of valproic acid and drug-mediated hepatotoxicity. Role of the terminal olefin, 2-n-propyl-4-pentenoic acid;Chem. Res. Toxicol.,1988

2. The porphyrias: Advances in diagnosis and treatment;Hematol. Am. Soc. Hematol. Educ. Program,2012

3. Formation of N-alkylprotoporphyrin IX from metabolism of diallyl sulfone in lung and liver;Drug Metab. Dispos.,2006

4. Liver metabolism of porphyrins and haem;J. Gastroenterol. Hepatol.,1998

5. Inactivation of multiple hepatic cytochrome P-450 isoenzymes in rats by allylisopropylacetamide: mechanistic implication;Mol. Pharmacol.,1987

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