Cytochrome P4501A1 Is Required for Vascular Dysfunction and Hypertension Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

Author:

Kopf Phillip G.,Scott Jason A.,Agbor Larry N.,Boberg Jason R.,Elased Khalid M.,Huwe Janice K.,Walker Mary K.

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Reference44 articles.

1. 2,3,7,8-Tetrachlorodibenzo-p-dioxin activation of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator pathway causes developmental toxicity through a CYP1A-independent mechanism in zebrafish;Mol. Pharmacol.,2004

2. Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress;Cardiovasc. Res.,2009

3. Targeted knockout of CYP1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery;Biochem. Biophys. Res. Commun.,2000

4. Dioxin exposure is an environmental risk factor for ischemic heart disease;Cardiovasc. Toxicol.,2001

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