From the Cover: Evaluation of the Effects of Tanezumab, a Monoclonal Antibody Against Nerve Growth Factor, on the Sympathetic Nervous System in Adult Cynomolgus Monkeys (Macaca fascicularis): A Stereologic, Histomorphologic, and Cardiofunctional Assessment
Author:
Affiliation:
1. Pfizer, Inc., San Diego, California 92121
2. Tox Path Specialists, LLC, Frederick, Maryland 21701
3. Pfizer, Inc., Groton, Connecticut 06340;
4. Pfizer, Inc., South San Francisco, California 94080
Publisher
Oxford University Press (OUP)
Subject
Toxicology
Link
http://academic.oup.com/toxsci/article-pdf/158/2/319/24194942/kfx089.pdf
Reference38 articles.
1. Analysis of the effects of the antiserum to the nerve growth factor in adult mice;Angeletti;Brain Res,1971
2. A non-human primate model for investigating drug-induced risk of orthostatic hypotension and sympathetic dysfunction: Preclinical correlate to a clinical test;Bhatt;J. Pharmacol. Toxicol. Methods,2015
3. A study of the de- and regenerative changes in the sympathetic nervous system of the adult mouse after treatment with the antiserum to nerve growth factor;Bjerre;Brain Res,1975
4. Developmental toxicity assessment of tanezumab, an anti-nerve growth factor monoclonal antibody, in cynomolgus monkeys (Macaca fascicularis);Bowman;Reprod. Toxicol,2015
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