Novel Nucleophiles Enhance the Human Serum Paraoxonase 1 (PON1)-mediated Detoxication of Organophosphates-Reference-Cited by-同舟云学术

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Novel Nucleophiles Enhance the Human Serum Paraoxonase 1 (PON1)-mediated Detoxication of Organophosphates

Published:2014-10-10 Issue:1 Volume:143 Page:46-53
ISSN:1096-0929
Container-title:Toxicological Sciences
language:en
Short-container-title:

Author:

Chambers Janice E.,Chambers Howard W.,Meek Edward C.,Funck Kristen E.,Bhavaraju Manikanthan H.,Gwaltney Steven R.,Pringle Ronald B.

Publisher

Oxford University Press (OUP)

Subject

Toxicology

Link

http://academic.oup.com/toxsci/article-pdf/143/1/46/16687519/kfu205.pdf

Reference30 articles.

1. Serum esterases. II. An enzyme hydrolyzing diethyl p-nitrophenol phosphate (E600) and its identity with the A-esterase of mammalian sera;Biochem. J.,1953

2. Unequal efficacy of pyridinium oximes in acute organophosphate poisoning;Clin. Med. Res.,2007

3. Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R;Arterioscler. Thromb. Vasc. Biol.,1998

4. A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: the RESP model;J. Phys. Chem.,1993

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1. Improved chemical synthesis, identification and evaluation of prospective centrally active oxime antidotes for the treatment of nerve agent exposure;Tetrahedron;2023-09

2. Fused human paraoxonase 1 as a prophylactic agent against organophosphate poisoning;Enzyme and Microbial Technology;2023-04

3. Paraoxonase 1 as a potential prophylactic against nerve agent poisoning;Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects;2023

4. Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase;Drug and Chemical Toxicology;2022-12-14

5. Novel pyridinium oximes enhance 24-h survivability against a lethal dose of nerve agent surrogate in adult female rats;Toxicology;2020-12

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