1. Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street , Toronto , ON M5S 3E1 , Canada
2. Department of Molecular Genetics, University of Toronto, 1 King's College Circle , Toronto , ON M5A 1A8 , Canada
3. Program in Genetics and Genome Biology, The Hospital for Sick Children , Toronto , ON Canada
4. Institute for Biomaterials and Biomedical Engineering, University of Toronto , Toronto , ON Canada