DNAforge: a design tool for nucleic acid wireframe nanostructures

Author:

Elonen Antti1ORCID,Wimbes Leon12ORCID,Mohammed Abdulmelik3ORCID,Orponen Pekka1ORCID

Affiliation:

1. Department of Computer Science, Aalto University , Finland

2. Department of Mathematics and Computer Science, Philipps University of Marburg , Germany

3. Department of Biomedical Engineering, San José State University , USA

Abstract

Abstract DNAforge is an online tool that provides a unified, user-friendly interface to several recent design methods for DNA and RNA wireframe nanostructures, with the possibility of integrating additional methods into the same framework. Currently, DNAforge supports three design methods for DNA nanostructures and two for RNA nanostructures. The tool enables the design, visualisation and sequence generation for highly complex wireframe nanostructures with a simple fully automated process. DNAforge is freely accessible at https://dnaforge.org/.

Funder

Finnish Cultural Foundation

Aalto University

Publisher

Oxford University Press (OUP)

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