How urban characteristics affect vulnerability to heat and cold: a multi-country analysis

Author:

Sera Francesco1,Armstrong Ben1,Tobias Aurelio2,Vicedo-Cabrera Ana Maria1,Åström Christofer3,Bell Michelle L4,Chen Bing-Yu5,de Sousa Zanotti Stagliorio Coelho Micheline6,Matus Correa Patricia7,Cruz Julio Cesar8,Dang Tran Ngoc910,Hurtado-Diaz Magali8,Do Van Dung9,Forsberg Bertil3,Guo Yue Leon511,Guo Yuming1213,Hashizume Masahiro14,Honda Yasushi15,Iñiguez Carmen16,Jaakkola Jouni J K1718,Kan Haidong19,Kim Ho20,Lavigne Eric2122,Michelozzi Paola23,Ortega Nicolas Valdes7,Osorio Samuel24,Pascal Mathilde25,Ragettli Martina S2627,Ryti Niilo R I1718,Saldiva Paulo Hilario Nascimento6,Schwartz Joel28,Scortichini Matteo23,Seposo Xerxes29,Tong Shilu303132,Zanobetti Antonella28,Gasparrini Antonio1

Affiliation:

1. Department of Public Health, Environments and Society, London School of Hygiene & Tropical Medicine, London, UK

2. Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council for Scientific Research (CSIC), Barcelona, Spain

3. Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden

4. School of Forestry and Environmental Studies, Yale University, New Haven, CT, USA

5. National Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan

6. Institute of Advanced Studies, University of São Paulo, São Paulo, Brazil

7. Department of Public Health, Universidad de los Andes, Santiago, Chile

8. Department of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico

9. Department of Environmental Health, Faculty of Public Health, University of Medicine and Pharmacy of Ho Chi Minh City, Ho Chi Minh City, Vietnam

10. Institute of Research and Development, Duy Tan University, Da Nang, Vietnam

11. Environmental and Occupational Medicine, National Taiwan University (NTU) and NTU Hospital, Taipei, Taiwan

12. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

13. Climate, Air Quality Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

14. Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

15. Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan

16. Department of Statistics and Computational Research, Environmental Health Research Joint Reseaech Unit FISABIO-UV-UJI CIBERESP, University of València, València, Spain

17. Medical Research Center Oulu (MRC Oulu), Oulu University Hospital and University of Oulu, Oulu, Finland

18. Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland

19. Department of Environmental Health, School of Public Health, Fudan University, Shanghai, China

20. Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea

21. School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada

22. Air Health Science Division, Health Canada, Ottawa, Canada

23. Department of Epidemiology, Lazio Regional Health Service, Rome, Italy

24. Department of Environmental Health, University of São Paulo, São Paulo, Brazil

25. Santé Publique France, Department of Environmental Health, French National Public Health Agency, Saint Maurice, France

26. Swiss Tropical and Public Health Institute, Basel, Switzerland

27. University of Basel, Basel, Switzerland

28. Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA

29. Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan

30. Shanghai Children’s Medical Centre, Shanghai Jiao-Tong University, Shanghai, China

31. School of Public Health and Institute of Environment and Human Health, Anhui Medical University, Hefei, China

32. School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia

Abstract

Abstract Background The health burden associated with temperature is expected to increase due to a warming climate. Populations living in cities are likely to be particularly at risk, but the role of urban characteristics in modifying the direct effects of temperature on health is still unclear. In this contribution, we used a multi-country dataset to study effect modification of temperature–mortality relationships by a range of city-specific indicators. Methods We collected ambient temperature and mortality daily time-series data for 340 cities in 22 countries, in periods between 1985 and 2014. Standardized measures of demographic, socio-economic, infrastructural and environmental indicators were derived from the Organisation for Economic Co-operation and Development (OECD) Regional and Metropolitan Database. We used distributed lag non-linear and multivariate meta-regression models to estimate fractions of mortality attributable to heat and cold (AF%) in each city, and to evaluate the effect modification of each indicator across cities. Results Heat- and cold-related deaths amounted to 0.54% (95% confidence interval: 0.49 to 0.58%) and 6.05% (5.59 to 6.36%) of total deaths, respectively. Several city indicators modify the effect of heat, with a higher mortality impact associated with increases in population density, fine particles (PM2.5), gross domestic product (GDP) and Gini index (a measure of income inequality), whereas higher levels of green spaces were linked with a decreased effect of heat. Conclusions This represents the largest study to date assessing the effect modification of temperature–mortality relationships. Evidence from this study can inform public-health interventions and urban planning under various climate-change and urban-development scenarios.

Funder

Medical Research Council—UK

Career Development Fellowship of Australian National Health and Medical Research Council

Ministry of Education of Spain

Research Council for Health

Academy of Finland

National Health Research Institutes of Taiwan

US Environmental Protection Agency Assistance Agreement

Publisher

Oxford University Press (OUP)

Subject

General Medicine,Epidemiology

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