1. Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic , Cleveland, OH 44195 , USA
2. Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University , Cleveland, OH 44195 , USA
3. Department of Molecular and Systems Biology , Geisel School of Medicine, , Hanover, NH 03755 , USA
4. Dartmouth College , Geisel School of Medicine, , Hanover, NH 03755 , USA