1. Broad Institute , Cambridge, MA 02142 , USA
2. Howard Hughes Medical Institute, Massachusetts General Hospital , Boston, MA 02114 , USA
3. Department of Molecular Biology, Massachusetts General Hospital , Boston, MA 02114 , USA
4. Department of Systems Biology, Harvard Medical School , Boston, MA 02115 , USA
5. Department of Anesthesia , Critical Care, and Pain Medicine, , Boston, MA 02114 , USA
6. Massachusetts General Hospital , Critical Care, and Pain Medicine, , Boston, MA 02114 , USA
7. Cardiology Division , Department of Medicine, , Boston, MA 02114 , USA
8. Massachusetts General Hospital , Department of Medicine, , Boston, MA 02114 , USA