Coumarin-based fluorescent probe synthesized by one-step reaction for sensitive detection of hydrazine and its application

Abstract

Abstract A coumarin-derivative fluorescent probe 3-(2-naphthyl)-7-acetoxycoumarin (TTAM) for hydrazine detection was successfully designed and synthesized. Hydrogen nuclear magnetic resonance (1H NMR) spectroscopy and high-resolution mass spectrometry showed that the nucleophilic substitution that occurred between hydrazine and the acyl oxide group of TTAM led to the probe fluorescence intensity increasing significantly and a remarkable color change that could be distinguished by using the naked eye. The reaction could be finished in 120 s and the detection limit was only 3.1 × 10−8 M. Moreover, a simple test paper was successfully developed that could be applied for the rapid detection of hydrazine in water samples.