Heterogeneous clinical phenotypes and cerebral malformations reflected by rotatin cellular dynamics

Author:

Vandervore Laura V123,Schot Rachel1,Kasteleijn Esmee1,Oegema Renske14,Stouffs Katrien23,Gheldof Alexander23,Grochowska Martyna M1,van der Sterre Marianne L T1,van Unen Leontine M A1,Wilke Martina1,Elfferich Peter1,van der Spek Peter J4,Heijsman Daphne14,Grandone Anna5,Demmers Jeroen A A6,Dekkers Dick H W6,Slotman Johan A7,Kremers Gert-Jan7,Schaaf Gerben J18,Masius Roy G1,van Essen Anton J9,Rump Patrick9,van Haeringen Arie10,Peeters Els11,Altunoglu Umut12,Kalayci Tugba12,Poot Raymond A13,Dobyns William B1415,Bahi-Buisson Nadia16,Verheijen Frans W1,Jansen Anna C2317,Mancini Grazia M S1

Affiliation:

1. Department of Clinical Genetics, Erasmus University Medical Center (Erasmus MC), CA Rotterdam, The Netherlands

2. Neurogenetics Research Group, Research Cluster Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel, Brussels, Belgium

3. Center for Medical Genetics, UZ Brussel, Brussels, Belgium

4. Department of Pathology, Clinical Bio-informatics, Erasmus University Medical Center (Erasmus MC), CA Rotterdam, The Netherlands

5. Dipartimento della Donna, del Bambino, di Chirurgia Generale e Specialistica, Seconda Università degli studi della Campania “L. Vanvitelli”, Naples, Italy

6. Department of Molecular Genetics, Proteomics Center, Erasmus University Medical Center (Erasmus MC), CA Rotterdam, The Netherlands

7. Department of Pathology, Optical Imaging Center, Erasmus University Medical Center (Erasmus MC), CA Rotterdam, The Netherlands

8. Center for Lysosomal and Metabolic Diseases, Erasmus Medical Center (Erasmus MC), 3015 CN Rotterdam, The Netherlands

9. Department of Genetics, University of Groningen, University Medical Center Groningen, RB, Groningen, The Netherlands

10. Department of Clinical Genetics, LUMC, Leiden University Medical Center, Postzone K-5-R, Postbus 9600, RC Leiden, The Netherlands

11. Department of Pediatric Neurology, Juliana Hospital, Els Borst-Eilersplein 275, 2545 AA Den Haag, The Netherlands

12. Department of Medical genetics, Istanbul Medical Faculty, Istanbul University, Topkapı Mahallesi, Turgut Özal Millet Cd, 34093 Fatih/İstanbul, Turkey

13. Department of Cell biology, Erasmus University Medical Center (Erasmus MC), CA Rotterdam, The Netherlands

14. Department of Pediatrics, University of Washington, Seattle, WA, USA

15. Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, WA, USA

16. Imagine Institute, INSERM UMR-1163, Laboratory Genetics and Embryology of Congenital Malformations, Paris Descartes University, Institut des Maladies Génétiques 24, Boulevard de Montparnasse, Paris, France

17. Pediatric Neurology Unit, Department of Pediatrics, UZ Brussel, Brussels, Belgium

Funder

Steunfonds Marguerite-Marie Delacroix, Research Foundation Flanders

COST Action

European Network on Brain Malformations, Neuro-MIG

Senior Clinical Investigator Fellowship

Research Foundation Flanders

FWO

ErasmusMC Mrace

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

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