Connectivity in ictal single photon emission computed tomography perfusion: a cortico-cortical evoked potential study

Author:

Tousseyn Simon12,Krishnan Balu1,Wang Zhong I.1,Wongwiangjunt Sattawut1,Nayak Chetan S.1,Mosher John C.1,Wu Guiyun1,Van Paesschen Wim3,Leahy Richard M.4,Gonzalez-Martinez Jorge A.1,Bulacio Juan1,Najm Imad M.1,Alexopoulos Andreas V.1,Nair Dileep R.1

Affiliation:

1. Epilepsy Center, Cleveland Clinic Foundation, Cleveland, OH, USA

2. Academic Center for Epileptology, Kempenhaeghe and Maastricht UMC+, Heeze, The Netherlands

3. Neurology Department, University Hospitals Leuven, Leuven, Belgium

4. University of Southern California, Los Angeles, CA, USA

Abstract

Ictal SPECT is used in presurgical evaluations of refractory epilepsy. Tousseyn et al. examine whether ictal perfusion changes correspond to electrically connected networks. Using evoked responses following direct electrical stimulation during stereo-electroencephalography as a connectivity measure, they show that ictal perfusion is not random but is supported by underlying connectivity.

Funder

Belgian American Educational Foundation

NIBIB

NINDS

NIH

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

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