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Monitoring clinical progression with mitochondrial disease biomarkers

Published:2017-08-03 Issue:10 Volume:140 Page:2530-2540
ISSN:0006-8950
Container-title:Brain
language:en
Short-container-title:

Author:

Steele Hannah E¹,Horvath Rita¹,Lyon Jon J²,Chinnery Patrick F³⁴

Affiliation:

1. Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK

2. GlaxoSmithKline, Molecular Safety and Disposition, Ware, SG12 0DP, UK

3. Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK

4. MRC Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK

Funder

National Institutes of Health

Wellcome Trust

NIHR

Medical Research Council

European Research Council

Newton Fund

GlaxoSmithKline

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Link

http://academic.oup.com/brain/article-pdf/140/10/2530/24174128/awx168.pdf

Reference132 articles.

1. ClinicalTrials.gov. Available from: https://clinicaltrials.gov/ (20 April 2017, date last accessed).

2. Metabolomic profiling of asthma and chronic obstructive pulmonary disease: a pilot study differentiating diseases;Adamko;J Allergy Clin Immunol,2015

3. Analytical methods in untargeted metabolomics: state of the art in 2015;Alonso;Front Bioeng Biotechnol,2015

4. A prototypical process for creating evidentiary standards for biomarkers and diagnostics;Altar;Clin Pharmacol Ther,2008

5. Abnormal myocardial energy-production state in mitochondrial cardiomyopathy and acute response to L-arginine infusion. C-11 acetate kinetics revealed by positron emission tomography;Arakawa;Circ J,2010

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