Magnetoencephalography imaging of high frequency oscillations strengthens presurgical localization and outcome prediction-Reference-Cited by-同舟云学术

Magnetoencephalography imaging of high frequency oscillations strengthens presurgical localization and outcome prediction

Published:2019-09-23 Issue:11 Volume:142 Page:3514-3529
ISSN:0006-8950
Container-title:Brain
language:en
Short-container-title:

Author:

Velmurugan Jayabal¹²³⁴^ORCID,Nagarajan Srikantan S⁴,Mariyappa Narayanan²,Mundlamuri Ravindranadh C³,Raghavendra Kenchaiah³,Bharath Rose Dawn⁵,Saini Jitender⁵,Arivazhagan Arimappamagan⁶,Rajeswaran Jamuna⁷,Mahadevan Anita⁸,Malla Bhaskara Rao⁶,Satishchandra Parthasarathy²³,Sinha Sanjib²³

Affiliation:

1. Department of Clinical Neurosciences, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

2. MEG Research Center, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

3. Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

4. Department of Radiology and Biomedical Imaging, University of California San Francisco (UCSF), San Francisco, USA

5. Department of NIIR, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

6. Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

7. Department of Neuropsychology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

8. Department of Pathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

Abstract

See van Klink and Zijlmans (doi:10.1093/brain/awz321) for a scientific commentary on this article. Velmuruganet al. report that detecting and localizing high‐frequency oscillations (HFOs: 80–200 Hz) with MEG can improve presurgical assessment and postsurgical outcome prediction in epilepsy. Source localization of HFOs identifies an epileptogenic region with accuracy of 75%. When such localized sources are surgically resected, patients have an approximately 80% probability of achieving seizure freedom.

Funder

TVS-NIMHANS bursary

Fulbright-Nehru India doctoral research fellowship

NIH

University of California

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

Link

http://academic.oup.com/brain/article-pdf/142/11/3514/30329979/awz284.pdf

Reference67 articles.