Presence of tau pathology within foetal neural allografts in patients with Huntington’s and Parkinson’s disease

Author:

Cisbani Giulia1,Maxan Alexander1,Kordower Jeffrey H2,Planel Emmanuel13,Freeman Thomas B45,Cicchetti Francesca13

Affiliation:

1. Centre de Recherche du CHU de Québec–Université Laval, Axe Neurosciences, 2705 Boulevard Laurier, Québec, QC, Canada

2. Department of Neurological Sciences and Center for Brain Repair, Rush University Medical Center, Chicago, IL 60612, USA

3. Département de Psychiatrie and Neurosciences, Université Laval, Québec, QC, Canada

4. Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, FL 33606-3571, USA

5. Center of Excellence for Aging and Brain Repair, University of South Florida, Tampa, FL 33606-3571, USA

Funder

Canadian Institutes of Health Research

CIHR

Alzheimer Society of Canada

Publisher

Oxford University Press (OUP)

Subject

Neurology (clinical)

Reference61 articles.

1. Relationship of neighboring tissue and gliosis to alpha-synuclein pathology in a fetal transplant for Parkinson's disease;Ahn;Am J Neurodegener Dis,2012

2. Tau hyperphosphorylation and oxidative stress, a critical vicious circle in neurodegenerative tauopathies?;Alavi Naini;Oxid Med Cell Longev,2015

3. Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo;Angot;PLoS One,2012

4. Neuronal plasticity in hibernation and the proposed role of the microtubule-associated protein tau as a “master switch” regulating synaptic gain in neuronal networks;Arendt;Am J Physiol Regul Integr Comp Physiol,2013

5. Transcellular spreading of huntingtin aggregates in the Drosophila brain;Babcock;Proc Natl Acad Sci USA,2015

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