Spatial and temporal manipulation of the Scn1a gene affect adult brain function
Author:
Affiliation:
1. Department of Human Genetics, Leiden University Medical Center , Leiden 2300 RC , The Netherlands
2. Department of Neurology, Leiden University Medical Center , Leiden 2300 RC , The Netherlands
Publisher
Oxford University Press (OUP)
Subject
Neurology (clinical)
Link
https://academic.oup.com/brain/advance-article-pdf/doi/10.1093/brain/awad422/56549297/awad422.pdf
Reference9 articles.
1. Temporal manipulation of the Scn1a gene reveals its essential role in adult brain function;Di Berardino;Brain
2. A transient developmental window of fast-spiking interneuron dysfunction in a mouse model of Dravet syndrome;Favero;J Neurosci,2018
3. Dravet variant SCN1A (A1783V) impairs interneuron firing predominantly by altered channel activation;Layer;Front Cell Neurosci,2021
4. Hippocampal deletion of NaV1.1 channels in mice causes thermal seizures and cognitive deficit characteristic of Dravet syndrome;Stein;Proc Natl Acad Sci U S A,2019
5. Focal and generalized seizure activity after local hippocampal or cortical ablation of NaV 1.1 channels in mice;Jansen;Epilepsia,2020
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1. Reply: Spatial and temporal manipulation of the Scn1a gene affect adult brain function;Brain;2023-12-14
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