Propofol-induced loss of consciousness is associated with a decrease in thalamocortical connectivity in humans-Reference-Cited by-同舟云学术

Propofol-induced loss of consciousness is associated with a decrease in thalamocortical connectivity in humans

Published:2019-06-24 Issue:8 Volume:142 Page:2288-2302
ISSN:0006-8950
Container-title:Brain
language:en
Short-container-title:

Author:

Malekmohammadi Mahsa¹^ORCID,Price Collin M¹,Hudson Andrew E²,DiCesare Jasmine A T¹,Pouratian Nader¹

Affiliation:

1. Department of Neurosurgery, University of California, Los Angeles, CA, USA

2. Department of Anaesthesiology, University of California, Los Angeles, CA, USA

Abstract

It is unclear how anaesthesia affects activity across brain networks. Using local field potentials recorded directly from the ventral intermediate nucleus of the thalamus and frontoparietal cortex in patients undergoing DBS surgery, Malekmohammadi et al. report the breakdown of α functional thalamocortical connectivity under propofol anaesthesia despite local power increases.

Funder

NIH

National Institutes of Biomedical Imaging and Bioengineering

National Institutes of Neurological Disorders and Stroke

Casa Colina Centers for Rehabilitation

National Institutes of General Medical Sciences

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

Link

http://academic.oup.com/brain/article-pdf/142/8/2288/31618187/awz169.pdf