NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice

Author:

Szczurkowska Joanna12,Pischedda Francesca3,Pinto Bruno14,Managò Francesca5,Haas Carola A6,Summa Maria7,Bertorelli Rosalia7,Papaleo Francesco5,Schäfer Michael K8,Piccoli Giovanni39,Cancedda Laura19

Affiliation:

1. Local Micro-environment and Brain Development Laboratory, Italian Institute of Technology, Genoa, Italy

2. Università degli Studi di Genova, Via Balbi, 5, 16126 Genoa, Italy

3. Laboratory of Biology of Synapse. Center for Integrative Biology (CIBIO), University of Trento, Trento, Italy

4. Bio@SNS, Scuola Normale Superiore, Pisa, Italy

5. Genetics of Cognition Laboratory, Italian Institute of Technology, Genoa, Italy

6. Experimental Epilepsy Research, Department of Neurosurgery, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

7. Department of Drug Discovery and Development, Italian Institute of Technology, Genoa, Italy

8. Department of Anesthesiology and Focus Program Translational Neurosciences, University Medical Center of the Johannes Gutenberg-University Mainz, Germany

9. Dulbecco Telethon Institute, Varese Street 16b - 00185 Rome, Italy

Funder

Telethon-Italy

CARIPLO foundation

European Research Council (ERC)

Publisher

Oxford University Press (OUP)

Subject

Clinical Neurology

Reference139 articles.

1. Relationship between soluble intercellular adhesion molecules and attention-deficit/hyperactivity disorder;Alasehirli;Int J Psychiatry Med,2015

2. PAK3 mutation in nonsyndromic X-linked mental retardation;Allen;Nat Genet,1998

3. Regulation of fibroblast growth factor receptor signalling and trafficking by Src and Eps8;Auciello;J Cell Sci,2013

4. A clinicopathological study of autism;Bailey;Brain,1998

5. Up-regulation of Ras/Raf/ERK1/2 signaling in the spinal cord impairs neural cell migration, neurogenesis, synapse formation, and dendritic spine development;Cao;Chin Med J,2013

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